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A new method for creating safer induced pluripotent stem cells(2017-05-24) [来源: http://www.eurekalert.org]
() Induced pluripotent stem cells (IPSCs) hold great promise in regenerative medicine, personalized medicine and drug discovery. However, while avoiding the ethical controversies associated with embryonic stem cells, they carry neoplastic risk owing to th...
Moffitt researchers demonstrate mathematical modeling limits aggressive tumor cell growth(2017-05-24) [来源: http://www.eurekalert.org]
() Researchers in the Integrated Mathematical Oncology Department at the Moffitt found that mathematical models can be used to predict how different tumor cell populations interact with each other and respond to a changing environment.
Revealed: How polyomavirus tricks our cells into helping it build its invasion route(2017-05-24) [来源: http://www.eurekalert.org]
() If every cell in our body is a factory, viruses are industrial spies who try to break in and take over. New findings about how one of the most mysterious types of spy - polyomaviruses -- accomplishes this feat could aid the fight against Merkel cell ca...
Harvard Medical School expert calls for protection of critical gains made in cancer care under ACA(2017-05-24) [来源: http://www.eurekalert.org]
() As the White House moves forward with its efforts to repeal Obamacare, it should strive to preserve -- and further boost -- these important advances, according to an introduction penned by Harvard Medical School professor health care policy expert Nanc...
Brain microenvironment makes HER2-positive breast cancer metastases resistant to treatment(2017-05-24) [来源: http://www.eurekalert.org]
() A Massachusetts General Hospital-based research team has identified a novel mechanism behind the resistance of breast cancer brain metastases to HER2- or PI3K-targeted therapies and a treatment strategy that may overcome this resistance.
BU researcher receives entrepreneur award from the American Thoracic Society(2017-05-24) [来源: http://www.eurekalert.org]
() Avrum Spira, MD, MSc, professor of medicine, pathology and bioinformatics at Boston University School of Medicine (BUSM), is the inaugural recipient of the Research Innovation and Translation Achievement Award from the American Thoracic Society (ATS).
AstraZeneca and the Francis Crick Institute sign research agreement(2017-05-23) [来源: http://www.eurekalert.org]
() The Francis Crick Institute has signed a new research agreement with global biopharmaceutical company AstraZeneca. The five-year initiative will see researchers from AstraZeneca and the Crick collaborate on early-stage research that could translate int...
Study offers guidance for targeting residual ovarian tumors(2017-05-23) [来源: http://www.eurekalert.org]
() MIT researchers who are working on an implantable device that could make intraperitoneal chemotherapy more bearable have published a new study that offers insight into how to improve chemotherapy strategies for ovarian cancer, and how to determine whic...
Increased lysyl oxidase may be a significant contributor to heart disease and cancer(2017-05-23) [来源: http://www.eurekalert.org]
() It's known that people with high blood pressure have increased levels of the enzyme lysyl oxidase (LOX), but it has not been clear if LOX actually contributes to heart disease. Now, a new research report appearing online in The FASEB Journal helps ...
Where body fat is carried can predict cancer risk(2017-05-23) [来源: http://www.eurekalert.org]
() Scientists have found that carrying fat around your middle could be as good an indicator of cancer risk as body mass index (BMI), according to research published in the British Journal of Cancer today.
Skin color no shield against skin cancer(2017-05-23) [来源: http://www.eurekalert.org]
() The misconception that people with more pigment -- called melanin -- in their skin cells are protected from cancer-causing ultra-violet rays can be deadly. Melanoma, the least common form of skin cancer but also the deadliest, are more likely to be ca...
A new T-cell population for cancer immunotherapy(2017-05-23) [来源: http://www.eurekalert.org]
() Scientists at the University of Basel in Switzerland have, for the first time, described a new T cell population that can recognize and kill tumor cells. The open access journal eLife has published the results.
Using a genetic signature to overcome chemotherapy-resistant lung cancer(2017-05-23) [来源: http://www.eurekalert.org]
() Patients with non-small cell lung cancer (NSCLC) often respond to standard chemotherapy, only to develop drug resistance later, and with fatal consequences. But what if doctors could identify those at greatest risk of relapse and provide a therapy to o...
Just one alcoholic drink a day increases breast cancer risk, exercise lowers risk(2017-05-23) [来源: http://www.eurekalert.org]
() A new report that analyzed the global scientific research on how diet, weight and exercise affect breast cancer risk finds there are steps women can take to lower their risk. The report finds that daily alcohol consumption and adult weight gain increas...
Tracking cancer's signaling pathways(2017-05-23) [来源: http://www.eurekalert.org]
() Malignant melanoma is one of the most common and dangerous types of cancer. Researchers at Friedrich-Alexander Universität Erlangen-Nürnberg investigated how and why brown pigmented moles turn into malignant melanoma using innovative robot technology. ...
CNIO researcher funded by Melanoma Research Alliance to study brain metastasis in melanoma(2017-05-22) [来源: http://www.eurekalert.org]
() Manuel Valiente, head of the Brain Metastasis Group at the Spanish National Cancer Research Centre (CNIO), has been funded in the 2017 grant cycle by the Melanoma Research Alliance (MRA), the largest private funder of melanoma research. The research, t...
Flexible new method for early cancer diagnosis(2017-05-22) [来源: http://www.eurekalert.org]
() Earlier discovery of cancer and greater precision in the treatment process are the objectives of a new method developed by researchers at Sahlgrenska Academy and Boston University. Investments are now being made to roll out this innovation across healt...
The secret to combating pancreatic cancer may lie in suppression of a common protein(2017-05-22) [来源: http://www.eurekalert.org]
() Research indicates that in mice with a KRAS mutation, present in 90 percent of pancreatic cancer patients, expressing only half the amount of the glucose-regulated protein GRP78 is enough to halt the earliest stage of pancreatic cancer development, res...
Black persons more likely than whites to be diagnosed with colon cancer, despite screening(2017-05-22) [来源: http://www.eurekalert.org]
() A study of elderly Medicare enrollees found that black persons face a 31 percent greater risk than white persons for interval colorectal cancer (CRC), or cancer that develops after a negative result on a colonoscopy but before the next recommended scre...
New cancer drug can prevent reactions to common airborne allergens(2017-05-22) [来源: http://www.eurekalert.org]
() A cancer drug for patients with certain types of leukemia and lymphoma can also prevent reactions to some of the most common airborne allergies, according to a recent Northwestern Medicine study. The promising data from this pilot study could have grea...
UTA's AbeXXa Biologics named one of 40 Best University Startups 2017 by NCET2(2017-05-22) [来源: http://www.eurekalert.org]
() AbeXXa Biologics, a faculty startup at The University of Texas at Arlington, was named one of the 40 'Best University Startups 2017' by the National Council of Entrepreneurial Tech Transfer. AbeXXa is identifying a new series of biomarkers or t...
Graphene-based sensor could improve evaluation, diagnosis and treatment of asthma(2017-05-22) [来源: http://www.eurekalert.org]
() Rutgers University-New Brunswick scientists have created a graphene-based sensor that could lead to earlier detection of looming asthma attacks and improve the management of asthma and other respiratory diseases, preventing hospitalizations and deaths.
Why fewer blood cancer patients receive hospice care(2017-05-22) [来源: http://www.eurekalert.org]
() Research has shown that patients with blood cancers are less likely to enroll in hospice care than patients with solid cancers, and the findings from a national survey suggest that concerns about the adequacy of hospice may prevent blood cancer special...
Raised blood platelet levels 'strong predictor' of cancer(2017-05-22) [来源: http://www.eurekalert.org]
() Having a high blood platelet count is a strong predictor of cancer and should be urgently investigated to save lives, according to a large-scale study.
An elegans solution: Worm genetic screen maps cell-to-cell communication in human cancer(2017-05-22) [来源: http://www.eurekalert.org]
() In the May 22, 2017, issue of Developmental Cell, researchers at the Medical University of South Carolina Hollings Cancer Center developed a cross-species genetic screen in worms to follow cell-to-cell communication in human cancer. The genome-wide scr...
Medical gamma-ray camera is now palm-sized(2017-05-22) [来源: http://www.eurekalert.org]
() Researchers invented a Compton camera of 580g which visualizes gamma rays of arbitrary energies, and succeeded in achieving a high-resolution, multicolor 3-D molecular image of a live mouse administered with three different radioactive tracers in just ...
Better, cheaper healthcare with dry blood samples(2017-05-22) [来源: http://www.eurekalert.org]
() A drop of blood on filter paper, allowed to dry and stored for future diagnostic purposes -- considerably easier than the present-day, resource-consuming method using frozen blood samples in plastic tubes. In a new study, Uppsala researchers have succe...
Doctors urge FDA to tighten regulations on 'filtered' cigarettes(2017-05-22) [来源: http://www.eurekalert.org]
() While the overall rate of lung cancer continues to decline in the United States, one form of the disease often found in the outer areas of the lungs continues to climb -- and experts think they know why.
Injecting activator of a powerful tumor suppressor directly into the cancer increases tumor destruction, decreases toxicity(2017-05-22) [来源: http://www.eurekalert.org]
() Directly injecting a tumor with an agent that activates a natural, powerful tumor suppressor enhances the drug's capacity to attack the tumor both locally and where it spreads, scientists report in the journal Cancer Research.
Educational session helps alleviate distress in prostate cancer patients & their partners(2017-05-19) [来源: http://www.eurekalert.org]
() In a recent study, an educational session helped alleviate distress equally in both patients with prostate cancer and their partners.
Rush clinical trial provides new kidney cancer immunotherapy option(2017-05-19) [来源: http://www.eurekalert.org]
() A new clinical trial provides a new option for kidney cancer patients and adds to Rush's wider research efforts towards identifying immune system biomarkers to better predict which immunotherapy will work best for individuals no matter which cancer...
One in 5 cancers diagnosed in the United States is a rare cancer(2017-05-19) [来源: http://www.eurekalert.org]
() About one in five cancer diagnoses in the United States is a rare cancer, according to a new American Cancer Society report.
Antibody for fighting cancer emerges(2017-05-19) [来源: http://www.eurekalert.org]
() While studying the underpinnings of multiple sclerosis, investigators at Brigham and Women's Hospital came across important clues for how to treat a very different disease: cancer. Researchers describe an antibody that can precisely target regulato...
The SNMMI Annual Meeting: Reaching new heights in the mile-high city(2017-05-18) [来源: http://www.eurekalert.org]
() The Society of Nuclear Medicine and Molecular Imaging's 2017 Annual Meeting will be held in Denver, Colorado, June 10-14. It will bring together more than 5,000 physicians, technologists, scientists and exhibitors from around the globe to share and...
Comprehensive cancer study assesses potential targets for personalized medicine and finds new ones(2017-05-18) [来源: http://www.eurekalert.org]
() A comprehensive approach confirmed molecular changes in cancer cells most likely involved in the development of the disease and discovered others that had not been typically linked to cancer before.
PharmaMar and STAsia sign licensing and marketing agreement for lurbinectedin(2017-05-18) [来源: http://www.eurekalert.org]
() PharmaMar (MSE:PHM) today announced an agreement with Singapore-based Specialised Therapeutics Asia Pte, Ltd (STA) to market the marine-based anti-tumour compound of the Company, lurbinectedin (PM1183) for the treatment of platinum-resistant ovarian ca...
Study estimates number of US women living with metastatic breast cancer(2017-05-18) [来源: http://www.eurekalert.org]
() A new study shows that the number of women in the United States living with distant metastatic breast cancer, the most severe form of the disease, is growing.
ASTRO's 59th Annual Meeting will explore the art and science of radiation oncology(2017-05-18) [来源: http://www.eurekalert.org]
() Registration opens today for the 59th Annual Meeting of the American Society for Radiation Oncology (ASTRO), which will highlight advances in cancer research and clinical care involving radiation therapy, also known as radiotherapy.
Cancer prevention & early detection, 2017-2018(2017-05-18) [来源: http://www.eurekalert.org]
() A new report assess cancer prevention measures in the United States and finds while there have been improvements in some areas, the use of potentially lifesaving measures is suboptimal.
Healthy lifestyle after colon cancer diagnosis helps patients live longer(2017-05-17) [来源: http://www.eurekalert.org]
() A study of 992 patients with stage III colon cancer found that those who reported a healthy lifestyle during and following adjuvant (post-surgery) treatment had a 42% lower chance of death and a trend for lower chance of cancer recurrence than those wh...
Oral chemotherapy extends survival by more than a year in biliary tract cancer(2017-05-17) [来源: http://www.eurekalert.org]
() A phase III randomized clinical trial of 447 patients with biliary tract cancers (BTCs, cancers of the bile duct and gallbladder) showed that giving capecitabine after surgery extends survival by a median of 15 months compared to surgery alone.
Cancer-cardiac connection illuminates promising new drug for heart failure(2017-05-17) [来源: http://www.eurekalert.org]
() A team of researchers at the Gladstone Institutes uncovered a new strategy to treat heart failure, a leading contributor to mortality and healthcare costs in the United States. Despite widespread use of currently-approved drugs, approximately 40 percen...
Researchers invented tools from flashes of light for controlling signalling circuits in living cells(2017-05-17) [来源: http://www.eurekalert.org]
() Researchers at Turku Centre for Biotechnology have invented new tools for decoding and controlling signalling circuits in living cells with flashes of light. In principle, any cellular circuit can now be targeted with the new method. By using this appr...
Early MRI may lower costs for prostate cancer treatment(2017-05-17) [来源: http://www.eurekalert.org]
() A diagnostic MRI followed by one of three MRI-guided biopsy strategies is a cost-effective method to detect prostate cancer, according to a new study out of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical C...
Number of mutations in a tumor varies by age and type of cancer(2017-05-17) [来源: http://www.eurekalert.org]
() A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that the tumor mutation load, or TML, in a patient's cancer biopsy varied by age and the type of cancer, along with several other factors.
Drug improves survival of patients with rare cancer by almost a quarter(2017-05-17) [来源: http://www.eurekalert.org]
() Patients who take capecitabine after surgery for bile duct cancer live for almost a year and a half longer than those not given the drug.
Researchers apply new immune technologies in search of mono vaccine(2017-05-17) [来源: http://www.eurekalert.org]
() With a recent 1.8 million, five-year grant from the National Institutes of Health, Brandon DeKosky's lab is using high-throughput techniques to analyze the behavior of B cells in the body.
Antibody that neutralizes sMIC boosts CTLA4 immunotherapy response and reduces colitis(2017-05-17) [来源: http://www.eurekalert.org]
() Co-administering a monoclonal antibody that neutralizes tumor-released sMIC improves anti-CTLA4 antibody therapy effectiveness and reduces treatment-related colitis, report Medical University of South Carolina investigators in an article published onli...
Deficiencies in repair of DNA identified in many types of solid tumors(2017-05-17) [来源: http://www.eurekalert.org]
() A new investigation of more than 48,000 stored tumor samples finds evidence of a key deficiency in a repair mechanism designed to keep DNA from being mutated and causing cancer.
Targeted therapy can delay recurrence of intermediate-stage lung cancer(2017-05-17) [来源: http://www.eurekalert.org]
() The targeted therapy gefitinib appears more effective in preventing recurrence after lung cancer surgery than the standard of care, chemotherapy.
Brigatinib first to offer over 1-year control of ALK-positive lung cancer post-crizotinib(2017-05-17) [来源: http://www.eurekalert.org]
() Results of a multi-center, 222-person phase 2 clinical trial of the next-generation ALK inhibitor, brigatinib at 180mg/day, used after failure of crizotinib showed a 54 percent response rate and 12.9 month progression-free survival.
Personalized medicine: The promise, the hype and the pitfalls(2017-05-17) [来源: http://www.eurekalert.org]
() Who owns your health data and why? Who really benefits from new cancer treatment development? Does personalised medicine live up to the hype? Does personalised medicine help us to know ourselves? What is the real-life value of precision medicine?
HPV vaccination may reduce oral HPV infections -- but still under-utilized(2017-05-17) [来源: http://www.eurekalert.org]
() In one of the first large studies to explore the possible impact of HPV vaccination on oral HPV infections, researchers found it may confer a high degree of protection. The study of young adults in the United States showed that the prevalence of high-r...
New imaging technique aims to ensure surgeons completely remove cancer(2017-05-17) [来源: http://www.eurekalert.org]
() A new imaging technique produces cellular images detailed enough for doctors to distinguish cancerous from normal tissue. The researchers are working on speeding up the new technique so it can be used during a surgery, allowing surgeons to find out whe...
Chance of colon cancer recurrence nearly cut in half in people who eat nuts(2017-05-17) [来源: http://www.eurekalert.org]
() An observational study of 826 patients with stage III colon cancer showed that those who consumed two ounces or more of nuts per week had a 42% lower chance of cancer recurrence and 57% lower chance of death than those who did not eat nuts.
A counterintuitive finding that could benefit younger colorectal cancer patients(2017-05-17) [来源: http://www.eurekalert.org]
() Younger colon cancer patients appear to have more than three times as many mutations in their tumors as older patients, which could lead to more effective treatment decisions, say researchers at Georgetown Lombardi Comprehensive Cancer Center.
More cancers diagnosed at early stage following increase in health insurance coverage(2017-05-17) [来源: http://www.eurekalert.org]
() An analysis of nearly 273,000 patients showed that between 2013 and 2014 there was a 1% increase in the percentage of breast, lung, and colorectal cancers diagnosed at the earliest, most treatable stage.
UC San Diego chemists create the ultimate natural sunscreen(2017-05-17) [来源: http://www.eurekalert.org]
() Chemists, materials scientists and nanoengineers at UC San Diego have created what may be the ultimate natural sunscreen.
PBS LearningMedia and Stand Up To Cancer announce 2017 Class of Emperor Science Awards(2017-05-17) [来源: http://www.eurekalert.org]
() One hundred high school students from 29 states are winners in the second year of PBS LearningMedia's and Stand Up To Cancer's Emperor Science Award program, an initiative designed to encourage high school students to explore careers cancer res...
New clinical trial framework tests 'natural' cures for cancer(2017-05-16) [来源: http://www.eurekalert.org]
() A University of Colorado Cancer Center clinical trial is now recruiting prostate cancer patients who would otherwise be on a watch-and-wait protocol to test the ability of grape seed extract to slow the rise of prostate-specific antigen (PSA), a common...
Tumor cells get stiff before becoming invasive(2017-05-16) [来源: http://www.eurekalert.org]
() A study published now on Nature Communications shows that breast cancer cells undergo a stiffening state prior to acquiring malignant features and becoming invasive. The discovery made by a research team led by Florence Janody, from Instituto Gulbenkia...
Complications from thyroid cancer surgery more common than believed, study finds(2017-05-16) [来源: http://www.eurekalert.org]
() As thyroid cancer rates rise, more people are having surgery to remove all or part of their thyroid. A new study suggests complications from these procedures are more common than previously believed.
3-D printed ovaries produce healthy offspring(2017-05-16) [来源: http://www.eurekalert.org]
() 3-D printed bioprosthetic mouse ovaries restored fertility in infertile mice and produced healthy mouse pups. The mothers also were able to nurse their pups. The research is targeted to women whose cancer treatments impaired their fertility and hormone...
Breast cancer risk is more affected by total body fat than abdominal fat(2017-05-16) [来源: http://www.eurekalert.org]
() A reduction in overall body fat, rather than abdominal fat, is associated with lower levels of breast cancer markers. The study published in Endocrine-Related Cancer, found that levels of several breast cancer risk markers were reduced in postmenopausa...
New finding affecting immune reconstitution related to B cells(2017-05-15) [来源: http://www.eurekalert.org]
() Researchers from the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles examined the mechanisms of B cell immune reconstitution in pediatric patients who had undergone bone marrow transplantation and discovered a...
Strategy significantly boosts colorectal screening for groups with low rates(2017-05-15) [来源: http://www.eurekalert.org]
() UNC Lineberger Comprehensive Cancer Center researchers and collaborators report in the Journal of the American Medical Association Internal Medicine that providing one-on-one support and customized tools for decision-making increased screening rates fo...
Decision aid, support strategy boosts colorectal testing for groups with low screening(2017-05-15) [来源: http://www.eurekalert.org]
() Helping patients understand colonoscopy alternatives and make a colorectal cancer screening choice based on their own values -- combined with one-on-one support -- dramatically increases screening completion among patients with historically lower scree...
Clinics should choose women's breast screening appointment times to improve attendance(2017-05-15) [来源: http://www.eurekalert.org]
() For women who miss a breast screening appointment, giving a fixed date and time for a new appointment could improve poor attendance and be a cost-effective way to shift national participation trends, according to an analysis led by Queen Mary Universit...
Tumor-trained T cells go on patrol(2017-05-15) [来源: http://www.eurekalert.org]
() In cancer, immune cells infiltrate tumors -- but it hasn't been known which immune cells exit the tumor or where they go next.Garvan researchers have shown that activated T cells are the main immune cell to leave tumors, and that these T cells move...
Metabolic peculiarities betray the identity of relapse-causing breast cancer cells(2017-05-15) [来源: http://www.eurekalert.org]
() Relapsing breast cancer is a leading cause of cancer-related death in women, and relapse-causing tumor cells are difficult to identify and target during remission. In a study published this week in the JCI, research led by Martin Jechlinger at the Euro...
Parents support policies to limit teens' access to indoor tanning(2017-05-15) [来源: http://www.eurekalert.org]
() Research led by Harvard Pilgrim Health Care Institute found that almost two-thirds (65 percent) of parents of adolescents agreed with policies to ban indoor tanning for youth under age 18. About one-quarter of parents had no opinion (23 percent), and o...
Scientists light the way for immune system to attack cancer(2017-05-15) [来源: http://www.eurekalert.org]
() The science behind harnessing the immune system to fight cancer is complicated, but a University of Rochester Medical Center laboratory discovered a simple, practical way to use light and optics to steer killer immune cells toward tumors.
Skin cancer on the rise(2017-05-15) [来源: http://www.eurekalert.org]
() New diagnoses for two types of skin cancer increased in recent years, according to a Mayo Clinic-led team of researchers.
WSU researchers deliver first 'nanotherapeutics' to tumor(2017-05-15) [来源: http://www.eurekalert.org]
() For the first time, WSU researchers have demonstrated a way to deliver a drug to a tumor by attaching it to a blood cell. The innovation could let doctors target tumors with anticancer drugs that might otherwise damage healthy tissues.
Prototype drug uses novel mechanism to treat lung cancers(2017-05-15) [来源: http://www.eurekalert.org]
() Lung cancer tumors were prevented in mice by a novel small molecule that directly activates a tumor suppressor protein.
Cell changes drive breast cancer relapse(2017-05-15) [来源: http://www.eurekalert.org]
() Relapse is now the main cause of death for breast cancer patients. Researchers at EMBL have found that, in mice, the tumor cells that survive therapy and eventually cause a relapse have specific traits that distinguish them from healthy cells. In a stu...
Simple post-surgery step significantly reduces bladder cancer recurrence(2017-05-15) [来源: http://www.eurekalert.org]
() It's just one step. Flushing the bladder with a common chemotherapy drug after a cancerous tumor is surgically removed reduces the chances of that cancer returning. Canadian and European clinical trials have proven this true and now a major US stud...
Study: New blood test is more accurate in predicting prostate cancer risk than PSA(2017-05-15) [来源: http://www.eurekalert.org]
() A team of researchers led by Cleveland Clinic have demonstrated that a new blood test known as IsoPSA detects prostate cancer more precisely than current tests in two crucial measures -- distinguishing cancer from benign conditions, and identifying pat...
Stem-cell transplants show limited benefit for double-hit lymphoma patients in remission(2017-05-15) [来源: http://www.eurekalert.org]
() Patients with double hit lymphoma (DHL) who undergo autologous stem-cell transplantation (autoSCT) after achieving remission are not more likely to remain in remission or live longer than patients who do not undergo autoSCT, according to a new analysis...
Natural defense mechanism preventing cancer at the earliest stage(2017-05-14) [来源: http://www.eurekalert.org]
() A new study shows cells in the initial stage of cancer change their metabolism before getting eliminated by the surrounding normal cells, providing a novel target for developing cancer prevention drugs.
New CDC-funded portal enables health providers to schedule free colon cancer screenings(2017-05-12) [来源: http://www.eurekalert.org]
() A new CDC-funded portal enables health providers to schedule free colorectal cancer screenings for uninsured patients in Cook County. Illinois Colon CARES, a UChicago Medicine-led initiative, is seeking to become model for other states to increase acc...
Ludwig researchers identify counterintuitive approach to treating a brain cancer(2017-05-12) [来源: http://www.eurekalert.org]
() The loss of the tumor suppressor gene PTEN has been linked to tumor growth and chemotherapy resistance in the almost invariably lethal brain cancer glioblastoma multiforme (GBM). Now, Ludwig researchers have shown that one way to override the growth-pr...
CSHL to lead international team developing next-generation organoid cancer research models(2017-05-11) [来源: http://www.eurekalert.org]
() CSHL has been awarded a research subcontract by Leidos Biomedical Research to lead a Cancer Model Development Center (CMDC) for pancreatic, breast, colorectal, lung, liver and other upper-gastrointestinal cancers. The new center will generate three-dim...
Cancer metastasis: The unexpected perils of hypoxia(2017-05-11) [来源: http://www.eurekalert.org]
() The low oxygen concentrations that prevail in many tumors enhance their propensity to metastasize to other tissues. Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich led by Professor Heiko Hermeking have now uncovered the molecular mechani...
World-first proton CT images create a new vision for cancer treatment(2017-05-11) [来源: http://www.eurekalert.org]
() An international team of scientists has produced the world's first computerized tomography (CT) images of biological tissue using protons -- a momentous step towards improving the quality and feasibility of Proton Therapy for cancer sufferers aroun...
New insights into the tumor metabolism(2017-05-11) [来源: http://www.eurekalert.org]
() Tumors, inflammation and circulatory disorders locally disturb the body's acid-base balance. These changes in pH value could be used for example to verify the success of cancer treatments. Up to now, however, there has been no imaging method to ren...
First study of Oncolytic HSV-1 in children & young adults with cancer indicates safety, tolerability(2017-05-11) [来源: http://www.eurekalert.org]
() HSV1716 -- an oncolytic herpes simplex virus-1 -- has been studied in adults via injection into the brain and superficial tumors. Now, a team of researchers at Nationwide Children's Hospital and Cincinnati Children's Hospital Medical Center hav...
Researchers identify nutrient metabolism that drives breast tumor metastasis(2017-05-11) [来源: http://www.eurekalert.org]
() A multinational group of scientists, led by professor Sarah-Maria Fendt (VIB-KU Leuven), have discovered that breast cancer cells that have invaded other organs rely on a different nutrient metabolism to produce energy than normal cells and non-metasta...
First spherical nucleic acid drug injected into humans targets brain cancer(2017-05-11) [来源: http://www.eurekalert.org]
() The first drug using spherical nucleic acids to be systemically given to humans has been developed by Northwestern University scientists and approved by the Food and Drug Administration as an investigational new drug for an early-stage clinical trial i...
Cutting smoking rates could save the NHS £67 million a year(2017-05-11) [来源: http://www.eurekalert.org]
() If smoking rates dropped to 5 percent in the UK by 2035, the NHS could save £67million in just one year, according to research published in Tobacco Control today.
A protein, a 'molecular staple' and CRISPR to develop an Ewing sarcoma model(2017-05-10) [来源: http://www.eurekalert.org]
() A team from the Spanish National Cancer Research Centre (CNIO) has optimized a system capable of generating a cellular model of Ewing sarcoma. The technique, based on CRISPR and described in the pages of Stem Cell Reports, makes it possible to generate...
Targeted, high-energy cancer treatments get a supercomputing boost(2017-05-10) [来源: http://www.eurekalert.org]
() Radiation therapy shoots high-energy particles into the body to destroy or damage cancer cells, while sparing surrounding healthy tissue. New types of radiation systems are emerging that can better target cancer cells. These include proton beam therapy...
Experimental technology monitors and maintains drug levels in the body(2017-05-10) [来源: http://www.eurekalert.org]
() A new technology can monitor and maintain the level of drug in the bloodstream of animals. If it works in people, it could deliver the optimal dose of life-saving drugs and prevent harmful over- or underdosing.
Team uncovers novel epigenetic changes in leukemia(2017-05-10) [来源: http://www.eurekalert.org]
() UT Health San Antonio researchers discovered epigenetic changes that contribute to one-fifth of cases of acute myeloid leukemia (AML), an aggressive cancer that arises out of the blood-forming cells in bone marrow. The mutations also play a role in a l...
Brain cancer discovery reveals clues in quest for new therapies(2017-05-10) [来源: http://www.eurekalert.org]
() Researchers at the University of Edinburgh have pinpointed two key molecules that drive the growth of an aggressive type of adult brain cancer. The findings shed light on the mechanisms that underpin brain cancer progression and could eventually reveal...
Scientists 'carbon date' cancer and unearth secrets about what could help make it deadly(2017-05-10) [来源: http://www.eurekalert.org]
() Scientists have put precise timings on the history of a patient's cancer for the first time, effectively 'carbon dating' the different stages in the disease's progression.Studying a single case of bowel cancer in great detail revealed t...
Tumor-dwelling immune cells thwart cancer immunotherapy(2017-05-10) [来源: http://www.eurekalert.org]
() Researchers have caught tumor-associated immune cells called macrophages in the act of stealing checkpoint inhibitor antibodies away from their intended T cell targets, and blocking this thievery led to improved therapeutic responses in tumor-bearing m...
Molecular imaging reveals mechanism for resistance to immune checkpoint blockade(2017-05-10) [来源: http://www.eurekalert.org]
() A study from Massachusetts General Hospital investigators has identified a surprising mechanism for resistance to immune checkpoint blockade. The study finds in a mouse model that an antibody-based drug designed to block the immunosuppressive molecule ...
Stem cell vaccine found to increase immune responses, inhibit tumors in animal models(2017-05-10) [来源: http://www.eurekalert.org]
() Researchers at the University of Cincinnati (UC) have found that a cancer stem cell vaccine, engineered to express a pro-inflammatory protein called interleukin-15 (IL-15) and its receptor (IL-15Ralpha), caused T cell production in animal models and en...
Tai chi relieves insomnia in breast cancer survivors(2017-05-10) [来源: http://www.eurekalert.org]
() Tai chi relieves insomnia in breast cancer survivors. New research shows that the slow-moving meditation practice -- frequently offered at community centers and libraries -- works just as well as talk therapy, and better than medication.



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